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Beilstein J. Org. Chem. 2020, 16, 2304–2313, doi:10.3762/bjoc.16.191
Graphical Abstract
Figure 1: Summary of the previous and present studies.
Scheme 1: Chan–Evans–Lam reaction of 4-trifluoromethylpyrimidin-2(1H)-one 1а with (het)aryl boronic acid 2b–w...
Scheme 2: Chan–Evans–Lam reaction of 4-trifluoromethylpyrimidin-2(1H)-one (1а) with (het)aryl- and alkenylbor...
Scheme 3: Chan–Evans–Lam reaction of pyrimidin-2(1H)-ones 1b–h with phenylboronic acid (2a).
Beilstein J. Org. Chem. 2017, 13, 2617–2625, doi:10.3762/bjoc.13.259
Figure 1: Summary of the present study.
Scheme 1: Hydrogenation of compounds 4–6 and preparation of N1(3)-unsubstituted compounds 9–11d.
Figure 2: Molecular structure of compound 11b. Two enantiomers form a heterochiral dimer in the crystal state...